Kratom and 7-OH-Mitragynine

Recorded November 9, 2025;

Faculty: Cornel N. Stanciu, MD, MRO, CPE, FASAM, FAPA, Addiction Psychiatrist & Assistant Professor of Psychiatry, Geisel School of Medicine, Dartmouth; Director of Addiction Services, New Hampshire Hospital)

Objectives:

1. Explain kratom’s pharmacology, emphasizing mitragynine and 7-hydroxymitragynine, their opioid-like and stimulant effects, and variability in product potency.

Faculty Bio:

Dr. Stanciu holds the position of Assistant Professor at Dartmouth’s Geisel School of Medicine and serves as the Director of Addiction Services at New Hampshire Hospital.
His accolades include being a former Ruth Fox scholar and Governors Institute on Substance Abuse scholar. He was appointed by New Hampshire’s governor to the Board of Medicine, Medical Review Subcommittee, and by the DHHS’s commissioner to the state’s Therapeutic Cannabis Medical Oversight Board. Additionally, he holds esteemed credentials as an ASAM and APA Fellow.
Throughout his distinguished career, Dr. Stanciu has been actively engaged in academia, with a significant publication record on topics related to addictive disorders. He has led multiple studies focused on understanding the clinical implications of Kratom and has contributed to the development of treatment guidelines for Kratom addiction. His research findings have been disseminated through presentations at numerous conferences, live webinars, and citations in scholarly literature. He serves on the editorial boards of several reputable journals and has received numerous awards for excellence in research and clinical care.
Dr. Stanciu maintains active involvement in professional organizations such as the APA, ASAM, and AAAP, where h: e presently serves as the Chief Editor for AAAP’s newsletter.
Furthermore, his commitment to advancing knowledge in the field is evident through his publication of the book titled “Deciphering the Addicted Brain: A Guide to understanding and Helping a Loved One Towards Recovery”.

Disclosures: Dr. Stanciu has nothing to disclose and the planners for this event have no financial relevant financial relationships to disclose.

CME: The Hanley Center for Health Leadership and Education designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This includes 1 credit that is compliant with New Hampshire RSA 318-B:40 - opioid education requirement.

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Hanley Center for Health Leadership and Education and NHMS. The Hanley Center for Health Leadership and Education is accredited by the Maine Medical Association Committee on Continuing Medical Education and Accreditation to provide continuing medical education for physicians.